Senior Physician I/II, Radiology
- Jing'an, Shanghai
- Permanent
- Full-time
- Reviews literature and consults with internal experts to identify biological mechanisms underlying pathophysiology and/or potential drug effects
- Assists in the design and execution of studies to assess biological mechanisms such as preparing pharmacogenetics components of clinical study protocols
- Liaises with colleagues in Clinical Pharmacology to assist in the design and execution of Phase I Clinical trials to establish Proof of Principle and to support Proof of Concept
- Initiates and monitors epidemiological research done by external scientific groups and provides medical/physician expertise to epidemiology colleagues who are not physicians
- Acts as a regional technical expert supporting the delivery of strategic input within the area of Physicians and provides consultancy within area of specialism
- Responsible for the safety evaluation in the early clinical trials, as well as the pharmacodynamic evaluation of the early compounds
- Delivers pharmacogenetics contribution to Translational Science Plans and Clinical Development Plans
- Supervises volunteers participating in medical trials and reviews safety assessments
- Leads the development of setting statistical standards or techniques in order that the quality, efficiency or effectiveness of projects are improved for overall Group efficiency
- Accountable for specialised research to enhance the effectiveness of Biostatistics contributions to worldwide submissions across a range of products
- Provides highly experienced strategic input, statistical expertise, and leadership to project teams in the design and interpretation of clinical studies and programmes of studies
- Applies expert physician skills to support internal proposal development and external regulatory submissions
- Acts as a source of knowledge in area of expertise, defining and communicating important initiatives across departments and functions
- Contributes to establishing and implementing policies, procedures and objectives for own work or team area to ensure compliance with both internal and external regulations
- Provides professional expertise to optimally design, analyse and interpret epidemiological studies and perform in depth epidemiological literature reviews
- Responsible for the safety evaluation in early clinical trials, as well as the proper pharmacodynamic evaluation of the early compounds
- Promotes good physician practice and ensures adherence with relevant protocols
- Develops operational systems and research processes across area of responsibility to increase the effectiveness and efficiency of projects
- Approximate number of people managed in total (all levels) - 10
- Matrix Manager – (projects/dotted line)
- Own country
- Essential: Bacherlor’s degree in medicine; Thorough knowledge of study analysis and design in all phases of drug development; Experience of modelling and simulation to improve execution of studies
- Desirable: Extensive general medical knowledge
- Internal (to AZ or team): Members of all functions on project team; Members of Development
- External (to AZ): External service providers; External regulatory agencies